Summary
Human life expectancy has been increasing steadily in most parts of the world. This improvement in human health is to be celebrated, but it is also revealing ageing to be the major risk factor for most diseases. Surprisingly, ageing has proved to be a malleable process, and health during ageing can be increased and lifespan extended in animals by genetic and environmental interventions. The mechanisms at work are highly conserved in evolution, and there are increasing indications that many age-related disease could be delayed or prevented by drugs, including existing drugs. This talk will discuss some of the recent discoveries, including the prospect for re-purposing existing drugs to protect against the effects of ageing.